How Does Tirzepatide Work?
Tirzepatide is unique because it activates both GLP-1 and GIP receptors, leading to:
- Stronger appetite suppression compared to GLP-1 alone
- More effective insulin and glucose control
- Increased fat oxidation and energy balance
- Prolonged satiety and reduced food intake
This dual-pathway mechanism makes Tirzepatide one of the most effective weight-loss peptides available today.
Usage & Administration
Tirzepatide is administered via subcutaneous (SubQ) injection, typically once per week.
Typical Dosage Recommendations
- Starting Dose: 2.5 mg per week (for 4 weeks) to minimize side effects
- Titration Phase: Increase to 5 mg per week (weeks 5-8)
- Effective Weight Loss Dose: 7.5-15 mg per week, depending on response
- Maintenance Dose: 10-15 mg per week, adjusted as needed
Note: A gradual increase in dosage helps minimize side effects while allowing the body to adapt.
As always, consult a medical professional before starting Tirzepatide.
Is Tirzepatide Safe?
Tirzepatide is FDA-approved and has undergone extensive clinical trials for both diabetes management and weight loss.
Potential Side Effects:
- Nausea & GI discomfort (most common, improves over time)
- Mild fatigue or dizziness
- Occasional constipation or diarrhea
- Rare risks include pancreatitis and thyroid issues (screening recommended before use)
Most side effects can be managed by slow dose titration and dietary modifications.